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dc.contributor.authorCatalan-Lopez, Sara
dc.contributor.authorCadarso-Suárez, Luis
dc.contributor.authorEsteves, Filipe
dc.contributor.authorSalgado-Borges, Jose
dc.contributor.authorLópez Ratón, Mónica
dc.contributor.authorCadarso Suárez, Carmen María
dc.date.accessioned2017-10-24T08:38:51Z
dc.date.available2017-10-24T08:38:51Z
dc.date.issued2016
dc.identifier.citationS. Catalan, L. Cadarso, F. Esteves, J. Salgado-Borges, M. Lopez, and C. Cadarso, “Assessment of Corneal Epithelial Thickness in Asymmetric Keratoconic Eyes and Normal Eyes Using Fourier Domain Optical Coherence Tomography,” Journal of Ophthalmology, vol. 2016, Article ID 5697343, 6 pages, 2016. doi:10.1155/2016/5697343
dc.identifier.issn2090-004X
dc.identifier.urihttp://hdl.handle.net/10347/16042
dc.description.abstractPurpose. To compare the characteristics of asymmetric keratoconic eyes and normal eyes by Fourier domain optical coherence tomography (OCT) corneal mapping. Methods. Retrospective corneal and epithelial thickness OCT data for 74 patients were compared in three groups of eyes: keratoconic (n=22) and normal fellow eyes (n=22) in patients with asymmetric keratoconus and normal eyes (n=104) in healthy subjects. Areas under the curve (AUC) of receiver operator characteristic (ROC) curves for each variable were compared across groups to indicate their discrimination capacity. Results. Three variables were found to differ significantly between fellow eyes and normal eyes (all < 0.05 ): minimum corneal thickness, thinnest corneal point, and central corneal thickness. These variables combined showed a high discrimination power to differentiate fellow eyes from normal eyes indicated by an AUC of 0.840 (95% CI: 0.762–0.918). Conclusions. Our findings indicate that topographically normal fellow eyes in patients with very asymmetric keratoconus differ from the eyes of healthy individuals in terms of their corneal epithelial and pachymetry maps. This type of information could be useful for an early diagnosis of keratoconus in topographically normal eyes
dc.language.isoeng
dc.publisherHindawi
dc.rights© 2016 S. Catalan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subject.classificationMaterias::Investigación::32 Ciencias médicas::3201 Ciencias clínicas::320109 Oftalmología
dc.titleAssessment of Corneal Epithelial Thickness in Asymmetric Keratoconic Eyes and Normal Eyes Using Fourier Domain Optical Coherence Tomography
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.1155/2016/5697343
dc.relation.publisherversionhttp://dx.doi.org/10.1155/2016/5697343
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.e-issn2090-0058
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Estatística, Análise Matemática e Optimización
dc.description.peerreviewedSI


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© 2016 S. Catalan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
Except where otherwise noted, this item's license is described as  © 2016 S. Catalan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited





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