Towards taxane analogues synthesis by dienyne ring closing metathesis
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Title: | Towards taxane analogues synthesis by dienyne ring closing metathesis |
Author: | Pérez-Estrada, S. Sayar, N. Granja Guillán, Juan Ramón |
Affiliation: | Universidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Moleculares Universidade de Santiago de Compostela. Departamento de Química Orgánica |
Subject: | Taxane | Ring closing metathesis | |
Date of Issue: | 2016-10-01 |
Publisher: | Royal Society of Chemistry |
Citation: | Pérez-Estrada, S.,Sayar, N. & Granja, J. (2017). Towards taxane analogues synthesis by dienyne ring closing metathesis . Org. Chem. Front., 2016,3, 1331-1336 . http://dx.doi.org/10.1039/C6QO00321D |
Abstract: | Herein we report the facile construction of taxadiene analogues by ring closing metathesis of dienynes built on a cyclohexenone with a natural configuration at C1 and its further transformation to incorporate most of the key functional groups of taxol |
Publisher version: | https://doi.org/10.1039/C6QO00321D |
URI: | http://hdl.handle.net/10347/17005 |
DOI: | 10.1039/C6QO00321D |
E-ISSN: | 2052-4129 |
Rights: | © The Royal Society of Chemistry 2016 |
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