Now showing items 19-21 of 21

    • Towards Ratiometric Sensing of Amyloid Fibrils In Vitro 

      Freire Rodríguez, Sonia; Rodríguez Prieto, María de la Flor; Ríos Rodríguez, María del Carmen; Penedo Esteiro, Juan Carlos; Al-Soufi, Wajih; Novo Rodríguez, María de la Merced (Wiley, 2015)
      The aggregation of amyloid‐β peptide and its accumulation in the human brain has an important role in the etiology of Alzheimer’s disease. Thioflavin T has been widely used as a fluorescent marker for these amyloid aggregates. ...
    • Ultrafast deactivation of bilirubin: dark intermediates and two-photon isomerization 

      Carreira Blanco, Carlos; Singer, Patrick; Diller, Rolf; Pérez Lustres, José Luis (Royal Society of Chemistry, 2016)
      Bilirubin is a neurotoxic product responsible for neonatal jaundice, which is generally treated by phototherapy. The photoreaction involves ultrafast internal conversion via an elusive intermediate and Z–E isomerization ...
    • Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents 

      Dalgarno, Paul A.; Juan-Colás, José; Hedley, Gordon J.; Piñeiro Maseda, Lucas; Novo Rodríguez, María de la Merced; Pérez González, Cibrán; Samuel, Ifor D. W.; Leake, Mark C.; Johnson, Steven; Al-Soufi, Wajih; Penedo, J. Carlos; Quinn, Steven D. (Nature Publishing Group, 2019)
      The solubilization of membranes by detergents is critical for many technological applications and has become widely used in biochemistry research to induce cell rupture, extract cell constituents, and to purify, reconstitute ...

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