Now showing items 1-3 of 3

    • Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism 

      Barros, Susana; Coimbra, Ana M.; Alves, Nélson; Pinheiro, Marlene; Quintana Álvarez, José Benito; Santos, Miguel Machado; Neuparth, Teresa (Taylor & Francis, 2020)
      Simvastatin (SIM), a hypocholesterolaemic drug belonging to the statins group, is a widely prescribed pharmaceutical for prevention of cardiovascular diseases. Several studies showed that lipophilic statins, as SIM, cross ...
    • Transcriptomic data on the transgenerational exposure of the keystone amphipod Gammarus locusta to simvastatin 

      Neuparth, Teresa; Machado, André M.; Montes Goyanes, Rosa María; Rodil Rodríguez, María del Rosario; Barros, Susana; Alves, Nélson; Ruivo, Raquel; Castro, Luis Filipe; Quintana Álvarez, José Benito; Santos, Miguel Machado (Elsevier, 2020)
      The use of transcriptomics data brings new insights and works as a powerful tool to explore the molecular mode of action (MoA) of transgenerational inheritance effects of contaminants of emerging concern. Therefore, in ...
    • Transgenerational inheritance of chemical-induced signature: A case study with simvastatin 

      Neuparth, Teresa; Machado, André M.; Montes Goyanes, Rosa María; Rodil Rodríguez, María del Rosario; Barros, Susana; Alves, Nélson; Ruivo, Raquel; Castro, Luis Filipe; Quintana Álvarez, José Benito; Santos, Miguel Machado (Elsevier, 2020)
      The hypothesis that exposure to certain environmental chemicals during early life stages may disrupt reproduction across multiple non-exposed generations has significant implications for understanding disease etiology and ...





      Harvesters:Useful links:
      Universidade de Santiago de Compostela | Teléfonos: +34 881 811 000 e +34 982 820 000 | Contact Us | Send Feedback