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dc.contributor.authorPazos Chantrero, Elena
dc.contributor.authorPortela Pallares, Cecilia
dc.contributor.authorPenas Tallón, Cristina
dc.contributor.authorVázquez Sentís, Marco Eugenio
dc.contributor.authorMascareñas Cid, José Luis
dc.date.accessioned2019-03-27T16:17:57Z
dc.date.available2019-03-27T16:17:57Z
dc.date.issued2015
dc.identifier.citationPazos, E., Portela, C., Penas, C., Vázquez, M., & Mascareñas, J. (2015). Peptide–DNA conjugates as tailored bivalent binders of the oncoprotein c-Jun. Org. Biomol. Chem., 13, 5385-5390. doi: 10.1039/c5ob00318k
dc.identifier.issn1477-0520
dc.identifier.urihttp://hdl.handle.net/10347/18491
dc.description.abstractWe describe a ds-oligonucleotide–peptide conjugate that is able to efficiently dismount preformed DNA complexes of the bZIP regions of oncoproteins c-Fos and c-Jun (AP-1), and therefore might be useful as disrupters of AP-1-mediated gene expression pathways
dc.description.sponsorshipWe thank the financial support provided by the Spanish grants SAF2010-20822-C02, SAF2013-41943-R and CTQ2012-31341, the Xunta de Galicia GRC2013-041 and the ERDF. E.P. thanks the Xunta de Galicia for her postdoctoral contract; C.P. and C.P. thank the Spanish Government for their Ph.D. fellowship
dc.language.isoeng
dc.publisherRoyal Society of Chemistry
dc.relationinfo:eu-repo/grantAgreement/MICINN/Plan Nacional de I+D+i 2008-2011/SAF2010-20822-C02/ES/DISEÑO Y DESARROLLO DE PROCESOS ENANTIOSELECTIVOS CATALIZADOS POR METALES DE TRANSICION PARA LA OBTENCION DE ESTRUCTURAS POLICICLICAS BIOLOGICAMENTE RELAVANTES
dc.relationinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2013-41943-R/ES/HERRAMIENTAS SINTETICAS EN QUIMICA BIOLOGICA. NUEVAS ESTRATEGIAS MOLECULARES PARA EL TRATAMIENTO Y DIAGNOSTICO DE CANCERES
dc.rights© The Royal Society of Chemistry 2015
dc.titlePeptide–DNA conjugates as tailored bivalent binders of the oncoprotein c-Jun
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.1039/C5OB00318K
dc.relation.publisherversionhttps://doi.org/10.1039/C5OB00318K
dc.type.versioninfo:eu-repo/semantics/acceptedVersion
dc.identifier.e-issn1477-0539
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Moleculares
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánica
dc.description.peerreviewedSI


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