Mostrar o rexistro simple do ítem

dc.contributor.advisorSánchez Piñón, Laura
dc.contributor.advisorMuinelo Romay, Laura
dc.contributor.advisorLópez López, Rafael
dc.contributor.advisorFacultade de Veterinaria
dc.contributor.authorCabezas Sáinz, Pablo
dc.date.accessioned2019-07-11T09:56:58Z
dc.date.available2019-07-11T09:56:58Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/10347/19114
dc.description.abstractZebrafish has emerged as one of the best models to characterize different human diseases due to his genetic similarity (75% of orthologous genes), and more specific, cancer. For this reason, zebrafish has been used in cancer research by means of the xenograft technique (injection of human cancer cells in embryos or adults of this model organism). The objective of this technique is simulate a human-like microenvironment inside a model organism in order to study the disease development with a fastest and accurate approach. As long as the xenograft technique has been implemented in zebrafish, mentioned before, there has been improvements to this technique and the conditions surrounding it. Nevertheless, there are some bottle necks with the necessity of being addressed with the objective of getting a more robust and informative technique in order to establish it in a near future in the personalized medicine field.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectZebrafish
dc.subjectCancer
dc.subjectXenograft
dc.subject.classificationMaterias::Investigación::24 Ciencias de la vida::2401 Biología animal (zoología)::240108 Genética animal
dc.subject.classificationMaterias::Investigación::32 Ciencias médicas::3207 Patología::320713 Oncología
dc.titleHCT116 colorectal and MCF7 brest cancer cell lines xenografted into zebrafish embryos gives insight into the importance of microenviroment in tumor growth and metastasis for a future use of the model in clinical research
dc.typedoctoral thesis
dc.rights.accessRightsopen access
dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro Internacional de Estudos de Doutoramento e Avanzados (CIEDUS)
dc.contributor.affiliationUniversidade de Santiago de Compostela. Escola de Doutoramento Internacional en Ciencias e Tecnoloxía
dc.contributor.affiliationUniversidade de Santiago de Compostela. Programa de Doutoramento en Medicina Molecular


Ficheiros no ítem

application/pdf
Nome: rep_1810
Tamaño: 33.30 Mb
Formato: PDF


Thumbnail

Este ítem aparece na(s) seguinte(s) colección(s)

Mostrar o rexistro simple do ítem

Attribution-NonCommercial-NoDerivatives 4.0 Internacional
A licenza do ítem descríbese como
 Attribution-NonCommercial-NoDerivatives 4.0 Internacional





Recolectores:Enlaces de interese:
Universidade de Santiago de Compostela | Teléfonos: +34 881 811 000 e +34 982 820 000 | Contacto | Suxestións