Microstructuring of materials with laser technologies for biomedical applications
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Title: | Microstructuring of materials with laser technologies for biomedical applications |
Author: | Aymerich López, María de la Inmaculada |
Advisor: | Flores Arias, María Teresa |
Affiliation: | Universidade de Santiago de Compostela. Centro Internacional de Estudos de Doutoramento e Avanzados (CIEDUS) Universidade de Santiago de Compostela. Escola de Doutoramento Internacional en Ciencias e Tecnoloxía Universidade de Santiago de Compostela. Programa de Doutoramento en Láser, Fotónica e Visión |
Subject: | laser ablation | microfluidic devices | laser matter interaction | |
Date of Issue: | 2019 |
Abstract: | This thesis presents the use of laser technologies for structuring different materials for applications in biomedicine. One of the aims of this work is the fabrication of fluidic chips for their employment as preclinical devices. By direct or indirect laser techniques, materials like soda-lime glass, titanium or tantalum are structured. Dimensions from microns to millimetres are achieved, depending on the final application of the chip. In particular, a device that imitates a coronary bifurcation is fabricated by laser technologies and soft-lithography methods. It is validated by culturing endothelial cells in their inner walls that withstand flow conditions. Other structures, like microchannels, a circulating tumour cells capturing chip or patterns over titanium and tantalum are manufactured. |
URI: | http://hdl.handle.net/10347/19464 |
Rights: | Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
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