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dc.contributor.authorRegueira López, Alberte
dc.contributor.authorBevilacqua, Riccardo
dc.contributor.authorLema Rodicio, Juan Manuel
dc.contributor.authorMauricio Iglesias, Miguel
dc.contributor.authorCarballa Arcos, Marta
dc.description.abstractMixed-culture fermentations (MCF) are recognised as a valid process to yield added-value products from organic wastes in the form of volatile fatty acids (VFA). The use of mixed cultures is attractive due to their economical and operational advantages (e.g. no sterilisation is needed). However, they also pose a fundamental challenge: they are complex and their regulation mechanisms remain still unclear. One of the main limitations of the process is its low product selectivity: the productivity of the different VFA is highly dependant on operational conditions (e.g. pH, retention time or feeding characteristics). In consequence, developing bioprocesses based on this technology remains a challenging task. In this context, we aim at establishing a model-based methodology for developing novel bioprocess using MCF. The emphasis is placed on two aspects: to reach a high productivity and a high selectivity on the desired VFA(s). The improvement of selectivity is carried out by means of a metabolic energy-based model while the productivity is maximised using a general kinetic-based model
dc.description.sponsorshipThe authors would like to acknowledge the support of the Spanish Ministry of Education (FPU14/05457) and ERA-IB-2 project BIOCHEM (PCIN 2016-102) funded by MINECO. The authors belong to the Galician Competitive Research Group ED431C2017/029 and to the CRETUS Stragetic Partnership (AGRUIP2017/01). All these programmes are co-funded by FEDER (UE)
dc.subjectVolatile fatty acids
dc.subjectMetabolic modelling
dc.subjectProtein fermentation
dc.subjectMixed culture fermentation
dc.subject.classificationMaterias::Investigación::33 Ciencias tecnológicas::3302 Tecnología bioquímica::330202 Tecnología de la fermentación
dc.subject.classificationMaterias::Investigación::33 Ciencias tecnológicas::3308 Ingeniería y tecnología del medio ambiente::330810 Tecnología de aguas residuales
dc.titleModelling the production of VFA from proteins by mixed culture fermentations
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Enxeñaría Química
dc.contributor.affiliationUniversidade de Santiago de Compostela. Instituto de Investigacións Tecnolóxicas

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