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dc.contributor.authorSánchez Molano, Enrique
dc.contributor.authorCerna, Álex
dc.contributor.authorToro Ibáñez, Miguel Ángel
dc.contributor.authorBouza Fernández, María Carmen
dc.contributor.authorHermida Prieto, Miguel
dc.contributor.authorGómez Pardo, María Belén
dc.contributor.authorCabaleiro, Santiago
dc.contributor.authorFernández Martín, Jesús
dc.contributor.authorMartínez Portela, Paulino
dc.date.accessioned2020-05-07T10:25:38Z
dc.date.available2020-05-07T10:25:38Z
dc.date.issued2011
dc.identifier.citationSánchez-Molano, E., Cerna, A., Toro, M.A. et al. Detection of growth-related QTL in turbot (Scophthalmus maximus). BMC Genomics 12, 473 (2011). https://doi.org/10.1186/1471-2164-12-473
dc.identifier.issn1471-2164
dc.identifier.urihttp://hdl.handle.net/10347/22120
dc.description.abstractBackground The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map in this species has allowed the selection of a panel of 100 homogeneously distributed markers covering the 26 linkage groups (LG) suitable for QTL search. In this study we addressed the detection of QTL with effect on body weight, length and Fulton's condition factor. Results Eight families from two genetic breeding programs comprising 814 individuals were used to search for growth related QTL using the panel of microsatellites available for QTL screening. Two different approaches, maximum likelihood and regression interval mapping, were used in order to search for QTL. Up to eleven significant QTL were detected with both methods in at least one family: four for weight on LGs 5, 14, 15 and 16; five for length on LGs 5, 6, 12, 14 and 15; and two for Fulton's condition factor on LGs 3 and 16. In these LGs an association analysis was performed to ascertain the microsatellite marker with the highest apparent effect on the trait, in order to test the possibility of using them for marker assisted selection. Conclusions The use of regression interval mapping and maximum likelihood methods for QTL detection provided consistent results in many cases, although the high variation observed for traits mean among families made it difficult to evaluate QTL effects. Finer mapping of detected QTL, looking for tightly linked markers to the causative mutation, and comparative genomics are suggested to deepen in the analysis of QTL in turbot so they can be applied in marker assisted selection programs.
dc.description.sponsorshipThis study was supported by the Consolider Ingenio Aquagenomics (CSD200700002), the Xunta de Galicia local Government (PGIDIT06RMA26101PR) and the Spanish Ministerio de Ciencia e Innovación (AGL2009-13273) projects. Belén G.Pardo is supported by Isidro Parga Pondal fellowship (Xunta de Galicia)
dc.language.isoeng
dc.publisherBMC
dc.rights© 2011 Sánchez-Molano et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
dc.rights.urihttp://creativecommons.org/licenses/by/2.0
dc.subjectLinkage Group
dc.subjectSyntenic Block
dc.subjectScophthalmus Maximus
dc.subjectAssociate Marker
dc.subjectAsian Seabass
dc.titleDetection of growth-related QTL in turbot (Scophthalmus maximus)
dc.typejournal article
dc.identifier.doi10.1186/1471-2164-12-473
dc.relation.publisherversionhttps://doi.org/10.1186/1471-2164-12-473
dc.type.hasVersionVoR
dc.rights.accessRightsopen access
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Xenética
dc.description.peerreviewedSI
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN/Plan Nacional de I+D+i 2008-2011/AGL2009-13273/ES/Extension Del Analisis Genomico Estructural En El Rodaballo: Mapeo Comparativo E Integracion Del Mapeo Genetico, Cromosomico Y Fisico
dc.relation.projectIDinfo:eu-repo/grantAgreement/MEC/Plan Nacional de I+D+i 2004-2007/CSD2007-00002/ES/Mejora de la producción en acuicultura mediante herramientas de biotecnología (Aquagenomics)


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© 2011 Sánchez-Molano et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
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 © 2011 Sánchez-Molano et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited





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