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dc.contributor.authorCastro País, Ana Isabel
dc.contributor.authorGómez Arbeláez, Diego Eduardo
dc.contributor.authorCrujeiras Martínez, Ana Belén
dc.contributor.authorGranero, Roser
dc.contributor.authorAguera, Zaida
dc.contributor.authorJiménez Murcia, Susana
dc.contributor.authorSajoux, Ignacio
dc.contributor.authorLópez Jaramillo, Patricio
dc.contributor.authorFernández Aranda, Fernando
dc.contributor.authorCasanueva Freijo, Felipe
dc.date.accessioned2020-05-12T12:12:49Z
dc.date.available2020-05-12T12:12:49Z
dc.date.issued2018
dc.identifier.citationCastro, A.I.; Gomez-Arbelaez, D.; Crujeiras, A.B.; Granero, R.; Aguera, Z.; Jimenez-Murcia, S.; Sajoux, I.; Lopez-Jaramillo, P.; Fernandez-Aranda, F.; Casanueva, F.F. Effect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients. Nutrients 2018, 10, 1348
dc.identifier.urihttp://hdl.handle.net/10347/22231
dc.description.abstractPsychological well-being and hunger and food control are two relevant factors involved in the success of weight-loss therapy in treating obesity. Thus, this study aims to evaluate food and alcohol cravings, physical and sexual activity, sleep, and life quality (QoL) in obese patients following a very low-calorie ketogenic (VLCK) diet, as well as the role of weight lost and ketosis on these parameters. A battery of psychological test was performed in twenty obese patients (12 females, 47.2 ± 10.2 year and BMI of 35.5 ± 4.4) through the course of a 4-month VLCK diet on four subsequent visits: baseline, maximum ketosis, reduced ketosis, and endpoint. Each subject acted as their own control. Relevantly, the dietary-induced changes in body composition (7.7 units of BMI lost, 18 kg of fat mass (1.2 kg of visceral fat mass)) were associated with a statistically significant improvement in food craving scores, physical activity, sleepiness, and female sexual function. Overall, these results also translated in a notable enhancement in QoL of the treated obese patients. Therefore, the rapid and sustained weight and fat mass (FM) loss induced by the VLCK diet is associated with good food control and improvements in the psychological well-being parameters in obese subjects, which could contribute to the long-term success of this therapy
dc.description.sponsorshipThis work was supported by grants from the Fondo de Investigacion Sanitaria, (PI14/01012 and PI17/01167) research projects and CIBERobn (CB06/003), from the Instituto de Salud Carlos III (ISCIII), Fondo Europeo de Desarrollo Regional (FEDER) Spanish. DGA is grateful to the Colombian Department of Science, Technology and Innovation—COLCIENCIAS as a recipient of their pre-doctoral scholarship to support his work. Ana B Crujeiras is funded by a research contract “Miguel Servet” (CP17/00088) from the ISCIII
dc.language.isoeng
dc.publisherMDPI
dc.rights© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectKetogenic diet
dc.subjectVery low-energy diet
dc.subjectPNK method
dc.subjectProtein diet
dc.subjectObesity
dc.subjectFood addition
dc.subjectSleep quality
dc.subjectSexual function
dc.subjectQoL
dc.titleEffect of A Very Low-Calorie Ketogenic Diet on Food and Alcohol Cravings, Physical and Sexual Activity, Sleep Disturbances, and Quality of Life in Obese Patients
dc.typejournal article
dc.identifier.doi10.3390/nu10101348
dc.relation.publisherversionhttps://doi.org/10.3390/nu10101348
dc.type.hasVersionVoR
dc.identifier.essn2072-6643
dc.rights.accessRightsopen access
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Psiquiatría, Radioloxía, Saúde Pública, Enfermaría e Medicina
dc.description.peerreviewedSI


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© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)
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 © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)





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