• Potent and subtype-selective dopamine D2 receptor biased partial agonists discovered via an Ugi-based approach 

  Mallo-Abreu, Ana; Reyes Resina, Irene; Azuaje Guerrero, Jhonny Alberto; Franco, Rafael; García Rey, Aitor; Majellaro, María; Miranda Pastoriza, Darío; García Mera, Xerardo Xusto; Jespers, Willem; Gutiérrez de Terán, Hugo; Navarro, Gemma; Sotelo, Eddy (ACS Publications, 2021)

  Using a previously unexplored, efficient, and versatile multicomponent method, we herein report the rapid generation of novel potent and subtype-selective DRD2 biased partial agonists. This strategy exemplifies the search ...

• Unveiling an NMR-invisible fraction of polymers in solution by saturation transfer difference 

  Novoa Carballal, Ramón; Martin-Pastor, Manuel; Fernandez-Megia, Eduardo (ACS Publications, 2021)

  The observation of signals in solution NMR requires nuclei with sufficiently large transverse relaxation times (T2). Otherwise, broad signals embedded in the baseline afford an invisible fraction of nuclei (IF). Based on ...

• Dynamic chiral PPA–AgNP nanocomposites: aligned silver nanoparticles decorating helical polymers 

  Nuñez Martínez, Manuel; Arias López, Sandra; Quiñoá Cabana, Emilio; Riguera Vega, Ricardo; Freire Iribarne, Félix Manuel (ACS Publications, 2021)

  A novel approach to prepare stimulus-sensitive nanocomposites is described, based on a dynamic helical polymer, chiral poly(phenylacetylene) (PPA), and silver nanoparticles. To preserve the dynamic helical behavior of PPA ...

• Merging supramolecular and covalent helical polymers: four helices within a single scaffold 

  Fernández Villar, Zulema; Fernández Rodríguez, Berta; Quiñoá Cabana, Emilio; Freire Iribarne, Félix Manuel (ACS Publications, 2021)

  Supramolecular and covalent polymers share multiple structural effects such as chiral amplification, helical inversion, sergeants and soldiers, or majority rules, among others. These features are related to the axial helical ...

• Tuning coherent-phonon heat transport in LaCoO3/SrTiO3 Superlattices 

  Rivadulla Fernández, José Francisco; Bugallo Ferrón, David; Langenberg Pérez, Eric; Carbo-Argibay, Enrique; Varela Domínguez, Noa; Otero Fumega, Adolfo; Pardo Castro, Víctor; Lucas del Pozo, Irene; Morellón Alquézar, Luis Alberto (ACS Publications, 2021)

  Accessing the regime of coherent phonon propagation in nanostructures opens enormous possibilities to control the thermal conductivity in energy harvesting devices, phononic circuits, etc. In this paper we show that coherent ...

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