Now showing items 1-6 of 6

    • Acute oral toxicity of tetrodotoxin in mice: determination of lethal dose 50 (LD50) and no observed adverse effect level (NOAEL) 

      Abal Camaño, Paula; Louzao Ojeda, María Carmen; Antelo Queijo, Álvaro; Alvarez, Mercedes; Cagide, Eva; Vilariño del Río, Natalia; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2017-02)
      Tetrodotoxin (TTX) is starting to appear in molluscs from the European waters and is a hazard to seafood consumers. This toxin blocks sodium channels resulting in neuromuscular paralysis and even death. As a part of the ...
    • Acute Toxicity Assessment: Macroscopic and Ultrastructural Effects in Mice Treated with Oral Tetrodotoxin 

      Abal Camaño, Paula; Louzao Ojeda, María Carmen; Vilariño del Río, Natalia; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2019)
      Tetrodotoxin (TTX) is an extremely toxic marine compound produced by different genera of bacteria that can reach humans through ingestion mainly of pufferfish but also of other contaminated fish species, marine gastropods ...
    • DSP Toxin Distribution across Organs in Mice after Acute Oral Administration 

      Louzao Ojeda, María Carmen; Abal Camaño, Paula; Costas Sánchez, Celia; Suzuki, Toshiyuki; Watanabe, Ryuichi; Vilariño del Río, Natalia; Botana López, Ana María; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (MDPI, 2021)
      Okadaic acid (OA) and its main structural analogs dinophysistoxin-1 (DTX1) and dinophysistoxin-2 (DTX2) are marine lipophilic phycotoxins distributed worldwide that can be accumulated by edible shellfish and can cause ...
    • In vitro and in vivo toxicity study of compounds of natural origin: marine biotoxins 

      Abal Camaño, Paula (2019)
      This doctoral thesis provides data on different phases necessary for a complete risk assessment of the most common marine biotoxins in Galicia: okadaic acid (OA), their derivatives the dinophysistoxins (DTXs), the azaspiracids ...
    • Serotonin involvement in okadaic acid-induced diarrhoea in vivo 

      Louzao Ojeda, María Carmen; Costas Sánchez, Celia; Abal Camaño, Paula; Suzuki, Toshiyuki; Watanabe, Ryuichi; Vilariño del Río, Natalia; Carrera González, María Cristina; Boente Juncal, Andrea; Vale González, María del Carmen; Rodríguez Vieytes, María Mercedes; Botana López, Luis Miguel (Springer, 2021)
      The consumption of contaminated shellfish with okadaic acid (OA) group of toxins leads to diarrhoeic shellfish poisoning (DSP) characterized by a set of symptoms including nausea, vomiting and diarrhoea. These phycotoxins ...
    • Study of Adsorption and Flocculation Properties of Natural Clays to Remove Prorocentrum lima 

      Louzao Ojeda, María Carmen; Abal Camaño, Paula; Fernández, Diego A.; Rodríguez Vieytes, María Mercedes; Legido, José Luis; Gómez, Carmen P.; Pais, Jesus; Botana López, Luis Miguel (MDPI, 2015)
      High accumulations of phytoplankton species that produce toxins are referred to as harmful algal blooms (HABs). HABs represent one of the most important sources of contamination in marine environments, as well as a serious ...





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