Browsing I+D+I by Author "be20e00c-1b83-4dd9-bca8-f0451494c552"
Now showing items 1-1 of 1
-
Through scaffold modification to 3,5-diaryl-4,5-dihydroisoxazoles: new potent and selective inhibitors of monoamine oxidase B
Meleddu, Rita; Distinto, Simona; Cirilli, Roberto; Alcaro, Stefano; Yañez Jato, Matilde; Sanna, María Luisa; Corona, Ángela; Melis, Claudia; Bianco, Giulia; Matyus, Peter; Cottiglia, Filippo; Maccioni, Elias (Taylor & Francis, 2017)3,5-Diaryl-4,5-dihydroisoxazoles were synthesized and evaluated as monoamine oxidase (MAO) enzyme inhibitors and iron chelators. All compounds exhibited selective inhibitory activity towards the B isoform of MAO in the ...