Browsing I+D+I by Title
Now showing items 21-40 of 17754
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3-O-Benzyl-6-O-benzoyl-1,2-Oisopropilidene-5-C-nitromethyl-a-Dglucofuranose
(International Union of Crystallography, 2008)The title compound, C24H27NO9, is one of the epimers of the Henry reaction of 3-O-benzyl-6-O-benzoyl-2-O-isopropylidene-a-D-glucofuran-5-one with nitromethane. The conformation of the five membered rings is as expected ... -
As 30 teses sobre ensino musical escolar desenvolvidas no Brasil de 1998 até 2017
(Universidad Federal de Minas Gerais, 2021)Esta pesquisa analisa o desenvolvimento da educação musical escolar como campo científico no Brasil. Após encontrarmos 300 teses de doutorado em educação musical defendidas no Brasil até 2017, realizamos um estudo de revisão ... -
3D evaluation of mandibular skeletal changes in juvenile arthritis patients treated with a distraction splint: A retrospective follow-up
(E.H Angle Education and Research Foundation, 2016)Objective: To evaluate three-dimensional (3D) condylar and mandibular growth in patients with juvenile idiopathic arthritis (JIA) with unilateral temporomandibular joint involvement treated with a distraction splint. Materials ... -
3D printed carboxymethyl cellulose scaffolds for autologous growth factors delivery in wound healing
(Elsevier, 2022)This work aims to use carboxymethyl cellulose (CMC) as main structural and functional component of 3D printed scaffolds for healing of diabetic wounds. Differently from previous inks involving small contents in CMC, herein ... -
3D printed pellets (miniprintlets): A novel, multi-drug, controlled release platform technology
(MDPI, 2019)[ENG]Selective laser sintering (SLS) is a single-step three-dimensional printing (3DP) process that can be leveraged to engineer a wide array of drug delivery systems. The aim of this work was to utilise SLS 3DP, for the ... -
3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients
(MDPI, 2020)Visual impairment and blindness affects 285 million people worldwide, resulting in a high public health burden. This study reports, for the first time, the use of three-dimensional (3D) printing to create orally disintegrating ... -
3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease
(MDPI, 2020)The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel ... -
3D Printing of a Multi-Layered Polypill Containing Six Drugs Using a Novel Stereolithographic Method
(MDPI, 2019)Three-dimensional printing (3DP) has demonstrated great potential for multi-material fabrication because of its capability for printing bespoke and spatially separated material conformations. Such a concept could revolutionise ... -
3D-printed alginate-hydroxyapatite aerogel scaffolds for bone tissue engineering
(Elsevier, 2021)3D-printing technology allows the automated and reproducible manufacturing of functional structures for tissue engineering with customized geometries and compositions by depositing materials layer-by-layer with high ... -
(4 + 2) Cycloadditions via Pd C(sp3 )–H activation
(Elsevier, 2021)The functionalization of aliphatic C (sp3)-H bonds using Pd catalysis has emerged as a powerful, step economical methodology for the construction of C–C and C–X bonds. Despite the progress in this field, examples of formal ... -
[4+2] and [4+3] catalytic cycloadditions of allenes
(Royal Society of Chemistry, 2014)This feature review describes the development of catalytic [4+2] and [4+3] cycloadditions of allenes, as efficient and practical methodologies for assembling six and seven-membered cyclic systems. The different methodologies ... -
5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines
(PLOS, 2019)The last fifteen years have seen the emergence and overflow into the drug scene of “superpotent” N-benzylated phenethylamines belonging to the “NBOMe” series, accompanied by numerous research articles. Although N-benzyl ... -
6 x 6: Novas tendencias da literatura e da ilustração portuguesas para a infância
(Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, 2010)Neste ensaio apresentaremos uma abordagem da produção literária e pictórica de seis autores e de seis ilustradores da nova geração, procurando destacar a novidade da sua criação, bem como as suas implicações ao nível ... -
A 6q14.1‐q15 microdeletion in a male patient with severe autistic disorder, lack of oral language, and dysmorphic features with concomitant presence of a maternally inherited Xp22.31 copy number gain
(Wiley, 2015)We report on a male patient with severe autistic disorder, lack of oral language, and dysmorphic features who carries a rare interstitial microdeletion of 4.96 Mb at chromosome 6q14.1‐q15. The patient also harbors a ... -
7 relatos curtos contra a violencia de xénero. I Concurso de relatos curtos contra a violencia de xénero
(Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, 2012)Con motivo da conmemoración do Día Internacional para a Eliminación da Violencia contra as Mulleres, a Universidade de Santiago de Compostela, a través da Oficina de Igualdade de Xénero, convocou o I Concurso de Relatos ... -
8-Propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one: A new coumarin with monoamine oxidase B inhibitory activity and possible anti-parkinsonian effects
(Universidade de São Paulo, 2020)Parkinson’s disease is a common neurodegenerative disorder. In this study, the monoamine oxidase inhibitory activity and potential anti-parkinsonian effects of 8-propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one (FCS303), a new ... -
8‐Aminomethyl‐7‐hydroxy‐4‐methylcoumarins as Multitarget Leads for Alzheimer's Disease
(Wiley, 2016-07-22)This work is part of our ongoing research in the discovery of multitarget therapeutic agents for Alzheimer's disease (AD). A literature screening, based on our recently proposed pharmacophore, led to the identification of ... -
9000 years of changes in peat organic matter composition in Store Mosse (Sweden) traced using FTIR-ATR
(Wiley, 2021)Store Mosse (the ‘Great Bog’ in Swedish) is one of the most extensive bog complexes in southern Sweden (~77 km2), where pioneering palaeoenvironmental research has been carried out since the early 20th century. This includes, ... -
9H-Dibenzo[a,c]carbazole from microwave assisted Madelung\'s reaction of N-[2-(phenylmethyl)phenyl]benzamide
(MDPI, 2009)Microwave irradiation of N-[2-(phenylmethyl)phenyl]benzamide with potassium tert-butoxide leads to a 1:1 ratio of the expected product from Madelung's reaction and 9H-Dibenzo[a,c]carbazole. This one seems to come from a ...