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dc.contributor.authorSilva, Marisa
dc.contributor.authorRodríguez Filgueiras, Inés
dc.contributor.authorBarreiro, Aldo
dc.contributor.authorKaufmann, Manfred
dc.contributor.authorNeto, Ana Isabel
dc.contributor.authorHassouani, Meryem
dc.contributor.authorSabour, Brahim
dc.contributor.authorAlfonso Rancaño, María Amparo
dc.contributor.authorBotana López, Luis Miguel
dc.contributor.authorVasconcelos, Vitor
dc.date.accessioned2020-11-06T11:01:07Z
dc.date.available2020-11-06T11:01:07Z
dc.date.issued2015
dc.identifier.citationSilva, M.; Rodriguez, I.; Barreiro, A.; Kaufmann, M.; Neto, A.I.; Hassouani, M.; Sabour, B.; Alfonso, A.; Botana, L.M.; Vasconcelos, V. New Invertebrate Vectors of Okadaic Acid from the North Atlantic Waters—Portugal (Azores and Madeira) and Morocco. Toxins 2015, 7, 5337-5347
dc.identifier.urihttp://hdl.handle.net/10347/23588
dc.description.abstractOkadaic acid and its analogues are potent phosphatase inhibitors that cause Diarrheic Shellfish Poisoning (DSP) through the ingestion of contaminated shellfish by humans. This group of toxins is transmitted worldwide but the number of poisoning incidents has declined over the last 20 years due to legislation and monitoring programs that were implemented for bivalves. In the summer of 2012 and 2013, we collected a total of 101 samples of 22 different species that were made up of benthic and subtidal organisms such echinoderms, crustaceans, bivalves and gastropods from Madeira, São Miguel Island (Azores archipelago) and the northwestern coast of Morocco. The samples were analyzed by UPLC-MS/MS. Our main objective was to detect new vectors for these biotoxins. We can report nine new vectors for these toxins in the North Atlantic: Astropecten aranciacus, Arbacia lixula, Echinaster sepositus, Holothuria sanctori, Ophidiaster ophidianus, Onchidella celtica, Aplysia depilans, Patella spp., and Stramonita haemostoma. Differences in toxin contents among the species were found. Even though low concentrations were detected, the levels of toxins that were present, especially in edible species, indicate the importance of these types of studies. Routine monitoring should be extended to comprise a wider number of vectors other than for bivalves of okadaic acid and its analogues
dc.description.sponsorshipThis research was partially funded by the FCT project UID/Multi/04423/2013 and by the projects MARBIOTECH (reference NORTE-07-0124-FEDER-000047) within the SR&TD Integrated Program MARVALOR—Building research and innovation capacity for improved management and valorization of marine resources, supported by the Programa Operacional Regional do Norte (ON.2-O Novo Norte) and NOVOMAR (reference 0687-NOVOMAR-1-P), supported by the European Regional Development Fund. MS acknowledge also FCT for the grant SFRH/BD/73269/2010 and Ana Regueiras, Isadora Diniz, Afonso Prestes and Manuela Maranhão. This research was also partially funded by the FCT-Portugal/CNRST-Morocco Cooperation Convention under the project 1006/13 CNR “Marine emergent toxins in the north east Atlantic (Portugal-Morocco) produced by microalgae and bacteria”. The research leading to USC results has received funding from the following FEDER cofunded-grants, from CDTI and Technological Funds. Supported by Ministerio de Economía y Competitividad, AGL2012-40185-CO2-01 and Consellería de Cultura, Educación e Ordenación Universitaria, GRC2013-016. Inés Rodriguez is supported by a fellowship from Subprograma de Formación de Personal Investigador (AGL2012-40185-CO2-01), Spain
dc.language.isoeng
dc.publisherMDPI
dc.rights© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectOkadaic acid
dc.subjectNew vectors
dc.subjectMadeira Island
dc.subjectSão Miguel Island
dc.subjectMorocco
dc.titleNew Invertebrate Vectors of Okadaic Acid from the North Atlantic Waters—Portugal (Azores and Madeira) and Morocco
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.3390/toxins7124885
dc.relation.publisherversionhttps://doi.org/10.3390/toxins7124885
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.e-issn2072-6651
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica
dc.description.peerreviewedSI


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© 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)
Except where otherwise noted, this item's license is described as  © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)





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