Trending Topics on Coumarin and Its Derivatives in 2020
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Título: | Trending Topics on Coumarin and Its Derivatives in 2020 |
Autor/a: | Carneiro Viqueira, Aitor Matos, Maria João Correia Pinto Carvalho de Uriarte Villares, Eugenio Santana Penín, María Lourdes |
Centro/Departamento: | Universidade de Santiago de Compostela. Departamento de Química Orgánica |
Palabras chave: | Coumarins | Biological applications | Drug discovery | Fluorescent probes | |
Data: | 2021 |
Editor: | MDPI |
Cita bibliográfica: | Molecules 2021, 26(2), 501; https://doi.org/10.3390/molecules26020501 |
Resumo: | Coumarins are naturally occurring molecules with a versatile range of activities. Their structural and physicochemical characteristics make them a privileged scaffold in medicinal chemistry and chemical biology. Many research articles and reviews compile information on this important family of compounds. In this overview, the most recent research papers and reviews from 2020 are organized and analyzed, and a discussion on these data is included. Multiple electronic databases were scanned, including SciFinder, Mendeley, and PubMed, the latter being the main source of information. Particular attention was paid to the potential of coumarins as an important scaffold in drug design, as well as fluorescent probes for decaging of prodrugs, metal detection, and diagnostic purposes. Herein we do an analysis of the trending topics related to coumarin and its derivatives in the broad field of drug discovery |
Versión do editor: | https://doi.org/10.3390/molecules26020501 |
URI: | http://hdl.handle.net/10347/24462 |
DOI: | 10.3390/molecules26020501 |
E-ISSN: | 1420-3049 |
Dereitos: | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/) Atribución 4.0 Internacional |
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