Pharmacological Extracts and Molecules from Virola Species: Traditional Uses, Phytochemistry, and Biological Activity
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Título: | Pharmacological Extracts and Molecules from Virola Species: Traditional Uses, Phytochemistry, and Biological Activity |
Autor/a: | González Rodríguez, María Ruiz Fernández, Clara Vera, Francisco Ait Eldjoudi, Djedjiga Ramadan Farrag Abdel Hafez, Yousof Cordero Barreal, Alfonso Pino Mínguez, Jesús Lago Paz, María Francisca Campos Toimil, Manuel Carvalho, Glaucimeire Rocha Pereira, Thiago Melo Costa Gualillo, Oreste |
Centro/Departamento: | Universidade de Santiago de Compostela. Centro de Investigación en Medicina Molecular e Enfermidades Crónicas Universidade de Santiago de Compostela. Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica |
Palabras chave: | Myristicaceae | Pharmacology | Phytotherapy | Virola surinamensis | Virola sebifera | Resin | Essential oil | Flavonoid | Lignan | Alkaloid | |
Data: | 2021 |
Editor: | MDPI |
Cita bibliográfica: | Molecules 2021, 26(4), 792; https://doi.org/10.3390/molecules26040792 |
Resumo: | Virola is the largest genus of Myristicaceae in America, comprising about 60 species of medium-sized trees geographically spread from Mexico to southern Brazil. The plant species of this genus have been widely used in folk medicine for the treatment of several ailments, such as rheumatic pain, bronchial asthma, tumors in the joints, intestinal worms, halitosis, ulcers, and multiple infections, due to their pharmacological activity. This review presents an updated and comprehensive summary of Virola species, particularly their ethnomedicinal uses, phytochemistry, and biological activity, to support the safe medicinal use of plant extracts and provide guidance for future research. The Virola spp.’s ethnopharmacology, including in the treatment of stomach pain and gastric ulcers, as well as antimicrobial and tryponosomicidal activities, is attributable to the presence of a myriad of phytoconstituents, such as flavonoids, tannins, phenolic acids, lignans, arylalkanones, and sitosterol. Hence, such species yield potential leads or molecular scaffolds for the development of new pharmaceutical formulations, encouraging the elucidation of not-yet-understood action mechanisms and ascertaining their safety for humans |
Versión do editor: | https://doi.org/10.3390/molecules26040792 |
URI: | http://hdl.handle.net/10347/24479 |
DOI: | 10.3390/molecules26040792 |
E-ISSN: | 1420-3049 |
Dereitos: | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/) Atribución 4.0 Internacional |
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- CIMUS-Artigos [249]
- FTF-Artigos [274]
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