Supramolecular strategies for intracellular delivery and design of new thermoresponsive materials
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Title: | Supramolecular strategies for intracellular delivery and design of new thermoresponsive materials |
Author: | Fernández Caro, Héctor |
Advisor: | Granja Guillán, Juan Ramón Montenegro García, Javier |
Affiliation: | Universidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS) Universidade de Santiago de Compostela. Programa de Doutoramento en Ciencia e Tecnoloxía Química |
Subject: | Supramolecular chemistry | Molecular recognition | Cyclodextrins | Gold nanoparticles | Cellpenetrating peptides | Cytosolic delivery | |
Date of Issue: | 2020 |
Abstract: | In this Ph.D. dissertation, we have applied supramolecular strategies to promote intracellular delivery of diverse molecules and design potential thermoresponsive systems. Host-guest chemistry has been exploited to encapsulate and deliver different anionic probes such as pyranine, as well as anionic peptides with low self-delivery efficiency. Finally, we have designed potential thermoresponsive supramolecular materials based on self-assembling cyclic peptide nanotubes (SCPNs). |
URI: | http://hdl.handle.net/10347/24499 |
Rights: | Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
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