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dc.contributor.advisor | Granja Guillán, Juan Ramón |
dc.contributor.advisor | Montenegro García, Javier |
dc.contributor.author | Fernández Caro, Héctor |
dc.date.accessioned | 2021-02-18T09:22:48Z |
dc.date.available | 2021-12-18T02:00:08Z |
dc.date.issued | 2020 |
dc.identifier.uri | http://hdl.handle.net/10347/24499 |
dc.description.abstract | In this Ph.D. dissertation, we have applied supramolecular strategies to promote intracellular delivery of diverse molecules and design potential thermoresponsive systems. Host-guest chemistry has been exploited to encapsulate and deliver different anionic probes such as pyranine, as well as anionic peptides with low self-delivery efficiency. Finally, we have designed potential thermoresponsive supramolecular materials based on self-assembling cyclic peptide nanotubes (SCPNs). |
dc.language.iso | eng |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
dc.subject | Supramolecular chemistry |
dc.subject | Molecular recognition |
dc.subject | Cyclodextrins |
dc.subject | Gold nanoparticles |
dc.subject | Cellpenetrating peptides |
dc.subject | Cytosolic delivery |
dc.subject.classification | Materias::Investigación::23 Química::2302 Bioquímica::230224 Péptidos |
dc.title | Supramolecular strategies for intracellular delivery and design of new thermoresponsive materials |
dc.type | doctoral thesis |
dc.rights.accessRights | embargoed access |
dc.contributor.affiliation | Universidade de Santiago de Compostela. Escola de Doutoramento Internacional (EDIUS) |
dc.contributor.affiliation | Universidade de Santiago de Compostela. Programa de Doutoramento en Ciencia e Tecnoloxía Química |
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Área de Ciencias [947]