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dc.contributor.authorGutiérrez Hernández, Sara
dc.contributor.authorTomás Gamasa, María
dc.date.accessioned2022-06-21T08:56:44Z
dc.date.available2022-06-21T08:56:44Z
dc.date.issued2022
dc.identifier.citationChem. Sci., 2022, 13, 6478-6495
dc.identifier.urihttp://hdl.handle.net/10347/28827
dc.description.abstractTranslating the power of transition metal catalysis to the native habitats of enzymes can significantly expand the possibilities of interrogating or manipulating natural biological systems, including living cells and organisms. This is especially relevant for organometallic reactions that have shown great potential in the field of organic synthesis, like the metal-catalyzed transfer of carbenes. While, at first sight, performing metal carbene chemistry in aqueous solvents, and especially in biologically relevant mixtures, does not seem obvious, in recent years there has been a growing number of reports demonstrating the feasibility of the task. Either using small molecule metal catalysts or artificial metalloenzymes, a number of carbene transfer reactions that tolerate aqueous and biorelevant media are being developed. This review intends to summarize the most relevant contributions, and establish the state of the art in this emerging research field
dc.language.isoeng
dc.publisherRoyal Society of Chemistry
dc.rights© 2022 The Author(s). Published by the Royal Society of Chemistry. This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence
dc.rightsAtribución-NoComercial 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.titleOrganometallic catalysis in aqueous and biological environments: harnessing the power of metal carbenes
dc.typeinfo:eu-repo/semantics/article
dc.identifier.DOI10.1039/d2sc00721e
dc.relation.publisherversionhttps://doi.org/10.1039/d2sc00721e
dc.type.versioninfo:eu-repo/semantics/publishedVersion
dc.identifier.e-issn1742-2183
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Moleculares
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánica
dc.description.peerreviewedSI


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© 2022 The Author(s). Published by the Royal Society of Chemistry. This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence
Except where otherwise noted, this item's license is described as  © 2022 The Author(s). Published by the Royal Society of Chemistry. This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence





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