Browsing Institutos e Centros de Investigación by Title
Now showing items 1-20 of 1778
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1,7-Naphthodiyne: a new platform for the synthesis of novel, sterically congested PAHs
(Royal Society of Chemistry, 2016-03-17)The synthesis of an efficient precursor of the novel 1,7-naphthodiyne synthon is reported. Preliminary experiments demonstrate the usefulness of this platform for the synthesis of sterically congested polyarenes, such as ... -
1D to 2D Self Assembly of Cyclic Peptides
(American Chemical Society, 2020)Despite recent developments in two-dimensional self-assembly, most supramolecular 2D materials are assembled by tedious methodologies, with complex surface chemistry and small sizes. We here report d/l-alternating cyclic ... -
[2+1] Cycloaddition of Catalytic Ruthenium Vinyl Carbenes: A Stereoselective Controlled Access to (Z)- and (E)-Vinyl Epoxypyrrolidines
(American Chemical Society, 2016)Aza-alkynals undergo a cyclization reaction with diazo compounds in the presence of catalytic amounts of Cp*RuCl(cod) to afford vinyl epoxypyrrolidines, valuable building blocks for the synthesis of biologically active ... -
26,26,26,27,27,27-Hexadeuterated-1,25-Dihydroxyvitamin D3 (1,25D-d6) As Adjuvant of Chemotherapy in Breast Cancer Cell Lines
(MDPI, 2013)It has been demonstrated that 1,25-dihydroxyvitamin D3 (1,25D) and some of its analogues have antitumor activity. 1,25D labeled with deuterium (26,26,26,27,27,27-hexadeuterated 1a,25-dihydroxyvitamin D3, or 1,25D-d6) is ... -
3D evaluation of mandibular skeletal changes in juvenile arthritis patients treated with a distraction splint: A retrospective follow-up
(E.H Angle Education and Research Foundation, 2016)Objective: To evaluate three-dimensional (3D) condylar and mandibular growth in patients with juvenile idiopathic arthritis (JIA) with unilateral temporomandibular joint involvement treated with a distraction splint. Materials ... -
(4 + 2) Cycloadditions via Pd C(sp3 )–H activation
(Elsevier, 2021)The functionalization of aliphatic C (sp3)-H bonds using Pd catalysis has emerged as a powerful, step economical methodology for the construction of C–C and C–X bonds. Despite the progress in this field, examples of formal ... -
[4+2] and [4+3] catalytic cycloadditions of allenes
(Royal Society of Chemistry, 2014)This feature review describes the development of catalytic [4+2] and [4+3] cycloadditions of allenes, as efficient and practical methodologies for assembling six and seven-membered cyclic systems. The different methodologies ... -
5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines
(PLOS, 2019)The last fifteen years have seen the emergence and overflow into the drug scene of “superpotent” N-benzylated phenethylamines belonging to the “NBOMe” series, accompanied by numerous research articles. Although N-benzyl ... -
8-Propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one: A new coumarin with monoamine oxidase B inhibitory activity and possible anti-parkinsonian effects
(Universidade de São Paulo, 2020)Parkinson’s disease is a common neurodegenerative disorder. In this study, the monoamine oxidase inhibitory activity and potential anti-parkinsonian effects of 8-propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one (FCS303), a new ... -
8‐Aminomethyl‐7‐hydroxy‐4‐methylcoumarins as Multitarget Leads for Alzheimer's Disease
(Wiley, 2016-07-22)This work is part of our ongoing research in the discovery of multitarget therapeutic agents for Alzheimer's disease (AD). A literature screening, based on our recently proposed pharmacophore, led to the identification of ... -
Ab initio investigation of the H2O2 + F elementary reaction
(Elsevier, 2016-07-01) -
Accounting for conformational flexibility and torsional anharmonicity in the H + CH3CH2OH hydrogen abstraction reactions: A multi-path variational transition state theory study
(AIP Publishing, 2014-05-06)This work reports a detailed theoretical study of the hydrogen abstraction reactions from ethanol by atomic hydrogen. The calculated thermal rate constants take into account torsional anharmonicity and conformational ... -
Accurate treatment of two-dimensional non-separable hindered internal rotors
(AIP Publishing, 2013-04-04)This work presents an accurate way for calculating partition functions of strongly coupled hindered rotors in two dimensions. The two-dimensional torsional potential is generated from electronic structure calculations and ... -
Unha achega ó estudo do proceso de codificación ortográfica e gramatical da lingua galega (1980-2000)
(Consello da Cultura GalegaInstituto da Lingua Galega, 2005) -
Achegamento ao perfil lingüístico dos autores dos inicios da Idade Contemporánea
(Consello da Cultura GalegaInstituto da Lingua Galega, 2012) -
Achegamento á antropotoponimia do concello de Vilalba (Lugo)
(Universidade de Santiago de Compostela, 2008)Das 28 parroquias que constitúen o concello de Vilalba (Lugo), até un total de 13 (aproximadamente o 46% do total) teñen como denominación un topónimo procedente dun antigo nome de posesor. Tentaremos analizar brevemente ... -
Achegamento á sintaxe dos falares mañego, lagarteiro e valverdeiro: o nivel frástico
(Consello da Cultura GalegaInstituto da Lingua Galega, 2004)Duns anos para acó a cantidade de estudos sobre a(s) lingua(s) das localidades cacereñas de S. Martiño de Trevello, As Ellas e Valverde experimentou un importante aumento. Así, e dentro das nosas fronteiras, ocupáronse ... -
Achegas para a edición crítica da Cantiga de Valcavado
(Universidade de Santiago de Compostela, 2008) -
Achegas para a morfoloxía do pronome acusativo de P3 e do artigo determinado en galego
(Consello da Cultura GalegaInstituto da Lingua Galega, 2004) -
Achegas recentes á cronoloxía do alomorfo nasal do clítico CD de 3ª persoa
(Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, 2015)Na esfera da cronoloxía dos cambios lingüísticos, o achado de novos textos antigos representa normalmente para a lingua galega unha oportunidade, moi esperada, de descubrir novas voces, novas acepcións, novos rexistros ...