Browsing Área de Ciencias da Saúde by Title
Now showing items 1-20 of 1111
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A 2-transcript host cell signature distinguishes viral from bacterial diarrhea and it is influenced by the severity of symptoms
(Nature Publishing Group, 2018)Recently, a biomarker signature consisting of 2-transcript host RNAs was proposed for discriminating bacterial from viral infections in febrile children. We evaluated the performance of this signature in a different disease ... -
2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients
(BMC, 2019)In the last three decades, Clostridium difficile infection (CDI) has increased in incidence and severity in many countries worldwide. The increase in CDI incidence has been particularly apparent among surgical patients. ... -
26,26,26,27,27,27-Hexadeuterated-1,25-Dihydroxyvitamin D3 (1,25D-d6) As Adjuvant of Chemotherapy in Breast Cancer Cell Lines
(MDPI, 2013)It has been demonstrated that 1,25-dihydroxyvitamin D3 (1,25D) and some of its analogues have antitumor activity. 1,25D labeled with deuterium (26,26,26,27,27,27-hexadeuterated 1a,25-dihydroxyvitamin D3, or 1,25D-d6) is ... -
3D printed pellets (miniprintlets): A novel, multi-drug, controlled release platform technology
(MDPI, 2019)[ENG]Selective laser sintering (SLS) is a single-step three-dimensional printing (3DP) process that can be leveraged to engineer a wide array of drug delivery systems. The aim of this work was to utilise SLS 3DP, for the ... -
3D Printed Tablets (Printlets) with Braille and Moon Patterns for Visually Impaired Patients
(MDPI, 2020)Visual impairment and blindness affects 285 million people worldwide, resulting in a high public health burden. This study reports, for the first time, the use of three-dimensional (3D) printing to create orally disintegrating ... -
3D Printed Tacrolimus Rectal Formulations Ameliorate Colitis in an Experimental Animal Model of Inflammatory Bowel Disease
(MDPI, 2020)The aim of this study was to fabricate novel self-supporting tacrolimus suppositories using semisolid extrusion 3-dimensional printing (3DP) and to investigate their efficacy in an experimental model of inflammatory bowel ... -
3D Printing of a Multi-Layered Polypill Containing Six Drugs Using a Novel Stereolithographic Method
(MDPI, 2019)Three-dimensional printing (3DP) has demonstrated great potential for multi-material fabrication because of its capability for printing bespoke and spatially separated material conformations. Such a concept could revolutionise ... -
5-HT2 receptor binding, functional activity and selectivity in N-benzyltryptamines
(PLOS, 2019)The last fifteen years have seen the emergence and overflow into the drug scene of “superpotent” N-benzylated phenethylamines belonging to the “NBOMe” series, accompanied by numerous research articles. Although N-benzyl ... -
8-Propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one: A new coumarin with monoamine oxidase B inhibitory activity and possible anti-parkinsonian effects
(Universidade de São Paulo, 2020)Parkinson’s disease is a common neurodegenerative disorder. In this study, the monoamine oxidase inhibitory activity and potential anti-parkinsonian effects of 8-propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one (FCS303), a new ... -
ABCDE approach to victims by lifeguards: How do they manage a critical patient? : A cross sectional simulation study
(PLOS, 2019)Introduction: Decision-making in emergencies is a multifactorial process based on the rescuer, patient, setting and resources. The eye-tracking system is a proven method for assessing decision-making processes that have ... -
Actinic Cheilitis prevalence and risk factors: a cross-sectional, multicentre study in a population aged 45 years and over in north-west Spain
(Society for Publication of Acta Dermato-Venereologica, 2018)Actinic cheilitis is thought to be a premalignant lesion or a superficial squamous cell carcinoma. The prevalence of actinic cheilitis in Europe is unknown. The aim of this study was to determine the prevalence of actinic ... -
Actinic cheilitis: analysis of clinical subtypes, risk factors and associated signs of actinic damage
(Acta Dermato-Venereologica, 2019)Actinic cheilitis (AC) is a common condition that mainly involves the lower lip, which is associated with chronic exposure to ultraviolet (UV) radiation. AC is considered a precursor of malignancy (1), but the rate of ... -
Action monitoring: correct and erroneous decisions are reflected in event-related potentials in humans
(2014-06-27)The main objective of this study is to understand the functional meaning of the error-related components. We have recorded the ERPs while human subjects performed in a perceptual length discrimination task (LDT) in which ... -
Actitudes ante la enfermedad en los estudiantes de medicina
(Universidade de Santiago de Compostela. Servizo de Publicacións e Intercambio Científico, 1994) -
Active or passive exposure to tobacco smoking and allergic rhinitis, allergic dermatitis, and food allergy in adults and children: a systematic review and meta-analysis
(PLOS, 2014)Background: Allergic rhinitis, allergic dermatitis, and food allergy are extremely common diseases, especially among children, and are frequently associated to each other and to asthma. Smoking is a potential risk factor ... -
Acumulación de selenio en setas silvestres comestibles: captación y toxicidad Selenium accumulation in wild edible mushrooms: uptake and toxicity
(Taylor & Francis, 2009)Los hongos acumulan selenio, metal considerado nutricionalmente oligoelemento, pero nocivo para la salud del consumidor en dosis excesivas. Se estudió el contenido de selenio en setas silvestres comestibles, teniendo en ... -
Acute Cardiotoxicity Evaluation of the Marine Biotoxins OA, DTX-1 and YTX
(MDPI, 2015)Phycotoxins are marine toxins produced by phytoplankton that can get accumulated in filter feeding shellfish. Human intoxication episodes occur due to contaminated seafood consumption. Okadaic acid (OA) and dynophysistoxins ... -
Acute muscle fatigue and CPR quality assisted by visual feedback devices: A randomized-crossover simulation trial
(PLOS, 2018-09-19)Objective: To analyse the acute muscular fatigue (AMF) in triceps brachii and rectus abdominis during compression-only and standard cardiopulmonary resuscitation (CPR) performed by certified basic life support providers. ... -
Acute onset supraclavicular lymphadenopathy coinciding with intramuscular mRNA vaccination against COVID-19 may be related to vaccine injection technique, Spain, January and February 2021
(European Centre for Disease Prevention and Control (ECDC), 2021)Monitoring adverse reactions following immunisation is essential, particularly for new vaccines such as those against COVID-19. We describe 20 cases of acute onset of a single supraclavicular lymphadenopathy manifesting ... -
Acute Toxicity Assessment: Macroscopic and Ultrastructural Effects in Mice Treated with Oral Tetrodotoxin
(MDPI, 2019)Tetrodotoxin (TTX) is an extremely toxic marine compound produced by different genera of bacteria that can reach humans through ingestion mainly of pufferfish but also of other contaminated fish species, marine gastropods ...