Now showing items 1-2 of 2
Insights into substrate binding and catalysis in bacterial type I dehydroquinase
(Portland Press, 2014-09-15)
Structural, biochemical and computational studies to study substrate binding and the role of the conserved residues of the DHQ1 (type I dehydroquinase) enzyme active site are reported in the present paper. The crystal ...
Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases
(Portland Press, 2014-03-15)
DHQ2 (type II dehydroquinase), which is an essential enzyme in Helicobacter pylori and Mycobacterium tuberculosis and does not have any counterpart in humans, is recognized to be an attractive target for the development ...