Now showing items 1-2 of 2

    • Advances on the formulation of proteins using nanotechnologies 

      Santalices Ramos, Irene; Gonella, Andrea; Torres López, María Dolores Ramona; Alonso Fernández, María José (Elsevier, 2017-12)
      Therapeutic proteins and peptides are very attractive from the pharmaceutical point of view due to their high potency and selectivity. Nonetheless, their instability and low bioavailability make their adminis- tration ...
    • Rational design of polyarginine nanocapsules intended to help peptides overcoming intestinal barriers 

      Niu, Zhigao; Tedesco, Erik; Benetti, Federico; Mabondzo, Aloïse; Montagner, Isabella Monia; Marigo, Ilaria; González Touceda, David; Tovar Carro, Sulay A.; Diéguez González, Carlos; Santander Ortega, Manuel J.; Alonso Fernández, María José (Elsevier, 2017)
      The aim of this work was to rationally design and characterize nanocapsules (NCs) composed of an oily core and a polyarginine (PARG) shell, intended for oral peptide delivery. The cationic polyaminoacid, PARG, and the oily ...

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