Now showing items 1-3 of 3

    • Advances on the formulation of proteins using nanotechnologies 

      Santalices Ramos, Irene; Gonella, Andrea; Torres López, María Dolores Ramona; Alonso Fernández, María José (Elsevier, 2017-12)
      Therapeutic proteins and peptides are very attractive from the pharmaceutical point of view due to their high potency and selectivity. Nonetheless, their instability and low bioavailability make their adminis- tration ...
    • Chitosan-Poly (I:C)-PADRE Based Nanoparticles as Delivery Vehicles for Synthetic Peptide Vaccines 

      Correia Pinto, Jorge F.; Csaba, Noemi Stefania; Schiller, John T.; Alonso Fernández, María José (MDPI, 2015)
      The safety and precision of peptide antigens has prompted the search for adjuvants capable of increasing the immune response against these intrinsically poorly immunogenic antigens. The integration of both immunostimulants ...
    • Polysaccharide nanoparticles can efficiently modulate the immune response against anHIV peptide antigen 

      Gómez Dacoba, Tamara; Omange, Robert W.; Li, Hongzhao; Crecente Campo, José; Luo, Ma; Alonso Fernández, María José (American Chemical Society, 2019)
      The development of an effective HIV vaccine continues to be a major health challenge since, so far, only the RV144 trial has demonstrated a modest clinical efficacy. Recently, the targeting of the 12 highly conserved ...

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