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GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: Elucidating potential anti-atherothrombotic targets in obesity
(Elsevier, 2019)
Background and aims: Platelets play a fundamental role in the increased atherothrombotic risk related to central obesity since they show hyperactivation and lower sensitivity to antiplatelet therapy in obese patients. The ...
Interspecies differences in protein expression do not impact the spatiotemporal regulation of glycoprotein VI mediated activation
(Wiley, 2019)
Accurate protein quantification is a vital prerequisite for generating meaningful predictions when using systems biology approaches, a method that is increasingly being used to unravel the complexities of subcellular ...
Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra
(MDPI, 2019)
So far, the Futuna Islands located in the Central Indo-Pacific Ocean have not been inventoried for their diversity in marine sponges and associated chemical diversity. As part of the Tara Pacific expedition, the first ...
Tetrodotoxins Occurrence in Non-Traditional Vectors of the North Atlantic Waters (Portuguese Maritime Territory, and Morocco Coast)
(MDPI, 2019)
Tetrodotoxin (TTX) is a potent alkaloid typically from tropical ecosystems, but in the last
decade its presence has been more pronounced in the temperate waters of the Atlantic. In its last
scientific opinion, the European ...
High serum cyclophilin C levels as a risk factor marker for coronary artery disease
(Nature Publishing Group, 2019)
Cyclophilins (Cyps) are ubiquitous proteins that belong to the immunophilins family consistently
associated with infammatory and cardiovascular diseases. While levels of CypA have been extensively
studied, less data are ...
Polysaccharide nanoparticles can efficiently modulate the immune response against anHIV peptide antigen
(American Chemical Society, 2019)
The development of an effective HIV vaccine continues to be a major health challenge since, so far, only the RV144 trial has demonstrated a modest clinical efficacy. Recently, the targeting of the 12 highly conserved ...
Syringeable Self-Organizing Gels that Trigger Gold Nanoparticle Formation for Localized Thermal Ablation
(MDPI, 2019)
Block copolymer dispersions that form gels at body temperature and that additionally are able to reduce a gold salt to nanoparticles (AuNPs) directly in the final formulation under mild conditions were designed as hybrid ...
Acute Toxicity Assessment: Macroscopic and Ultrastructural Effects in Mice Treated with Oral Tetrodotoxin
(MDPI, 2019)
Tetrodotoxin (TTX) is an extremely toxic marine compound produced by different genera of bacteria that can reach humans through ingestion mainly of pufferfish but also of other contaminated fish species, marine gastropods ...
Data on hyper-activation of GPVI signalling inobese patients: towards the identification ofnovel antiplatelet targets in obesity
(Elsevier, 2019)
This data article is associated with the manuscript "GPVI surface expression and signalling pathway activation are increased in platelets from obese patients: elucidating potential anti-atherothrombotic targets in obesity" ...
LC–MS/MS Analysis of the Emerging Toxin Pinnatoxin-G and High Levels of Esterified OA Group Toxins in Galician Commercial Mussels
(MDPI, 2019)
The occurrence of marine harmful algae is increasing worldwide and, therefore,
the accumulation of lipophilic marine toxins from harmful phytoplankton represents a food safety threat
in the shellfish industry. Galicia, ...