Now showing items 1-4 of 4
Self-assembled hyaluronan nanocapsules for the intracellular delivery of anticancer drugs
(Nature Publishing Group, 2019)
Preparation of sophisticated delivery systems for nanomedicine applications generally involve multi-step procedures using organic solvents. In this study, we have developed a simple self-assembling process to prepare ...
Engineering, on-demand manufacturing, and scaling-up ofpolymeric nanocapsules
Polymeric nanocapsules are versatile delivery systems with the capacity to load lipophilic drugs in their oily nucleus and hydrophilic drugs in their polymeric shell. The objective of this work was to expand the technological ...
Co-delivery of RNAi and Chemokine by Polyarginine Nanocapsules Enables the Modulation of Myeloid-Derived Suppressor Cells
Myeloid-Derived Suppressor Cells (MDSCs), immunosuppressive cells that promote tumor growth, represent an attractive target in cancer immunotherapy. However, the clinical success of this strategy is limited by the lack of ...
Polysaccharide nanoparticles can efficiently modulate the immune response against anHIV peptide antigen
(American Chemical Society, 2019)
The development of an effective HIV vaccine continues to be a major health challenge since, so far, only the RV144 trial has demonstrated a modest clinical efficacy. Recently, the targeting of the 12 highly conserved ...