Fisioloxía
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Detection of mycotoxins in cheese using an optimized analytical method based on a QuEChERS extraction and UHPLC-MS/MS quantification
(Elsevier, 2022)Mycotoxins can produce toxic effects on humans; hence, it is of high importance to determine their presence in food products. This work presents a reliable method for the quantification of 32 mycotoxins in cheese. The ... -
Enniatins A1 and B1 alter calcium homeostasis of neuronal cells leading to apoptotic death
(Elsevier, 2022)Enniatins (ENNs) A1 and B1 are non-regulated mycotoxins produced by Fusarium spp. that commonly occur in different types of food. These toxins are cytotoxic in several cell lines, but their mechanism of action is unclear. ... -
Silver clusters of five atoms as highly selective antitumoral agents through irreversible oxidation of thiols
(Wiley, 2022)Low atomicity clusters present properties dependent on the size, due to the quantum confinement, with well-defined electronic structures and high stability. Here it is shown that Ag5 clusters catalyze the complete oxidation ... -
Activation of hypothalamic AMP-activated protein kinase ameliorates metabolic complications of experimental arthritis
(Wiley, 2021)Objective: To investigate whether thermogenesis and the hypothalamus may be involved in the physiopathology of experimental arthritis (EA). Methods: EA was induced in male Lewis rats by intradermal injection of Freund's ... -
Development of a biosensor based on a new marine luciferase fused to an affibody to assess Her2 expression in living cells
(Elsevier, 2022)The development of new diagnostic tools in tumor pathology allows the optimization of individualized therapies in cancer patients. The functional optical image provides a unique opportunity to identify the pathophysiological ...