Now showing items 1-11 of 11

    • Aqueous Stable Gold Nanostar/ZIF‐8 Nanocomposites for Light‐Triggered Release of Active Cargo Inside Living Cells 

      Carrillo Carrión, Carolina; Martínez González, Raquel; Navarro Poupard, María Fernanda; Pelaz García, Beatriz; Polo Tobajas, Ester; Arenas-Vivo, Ana; Olgiati, Alessandro; Taboada Antelo, Pablo; Soliman, Mahmoud G.; Catalán, Úrsula; Fernández-Castillejo, Sara; Solà, Rosa; Parak, Wolfgang J.; Horcajada, Patricia; Alvarez-Puebla, Ramon A.; Pino, Pablo del (Wiley, 2019-05-20)
      A plasmonic core–shell gold nanostar/zeolitic‐imidazolate‐framework‐8 (ZIF‐8) nanocomposite was developed for the thermoplasmonic‐driven release of encapsulated active molecules inside living cells. The nanocomposites were ...
    • Characterization of Hydrogels for Their Application in Tissue Regeneration 

      Velasco Rodríguez, Brenda; Rosales Rivera, Luis Carlos; Soltero Martinez, José Félix Armando; Figueroa Velarde, Valeria; Pardo Montero, Alberto; Barbosa Fernández, Silvia; Taboada Antelo, Pablo (MDPI, 2021)
      Alterations in neurogenesis result in the inevitable loss of brain nervous tissue and cause neurodegenerative diseases, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and Huntington’s disease (HD). In this ...
    • Filling Tricompartmental Ligands with GdIII and ZnII Ions: Some Structural and MRI Studies 

      Corredoira Vázquez, Julio; Fondo Busto, María Matilde; Sanmartín Matalobos, Jesús; Taboada Antelo, Pablo; García Deibe, Ana María (MDPI, 2018)
      Here we report the synthesis and characterization of a mononuclear gadolinium complex (Gd) and two heteronuclear Zn-Gd complexes (ZnGd and Zn2Gd), which contain two similar three-armed ligands that display an external ...
    • Gold Nanorod-Based Nanohybrids for Combinatorial Therapeutics 

      Villar Álvarez, Eva María; Cambón Freire, Adriana; Pardo Montero, Alberto; Mosquera Rodríguez, Víctor; Bouzas Mosquera, Alberto; Topete Camacho, Antonio; Barbosa Fernández, Silvia; Taboada Antelo, Pablo; Mosquera Tallón, Víctor (American Chemical Society, 2018)
      In this work, multifunctional nanocarriers consisting of poly(sodium-4-styrenesulfonate) (PSS)/doxorubicin (DOXO)/poly-l-lysine hydrobromide (PLL)/hyaluronic acid (HA)-coated and (PSS/DOXO/PLL)2/HA-coated gold nanorods ...
    • A heteronuclear ZnGd complex as a potential contrast agent for magnetic resonance imaging 

      Fondo Busto, María Matilde; Corredoira Vázquez, Julio; García Deibe, Ana María; Sanmartín Matalobos, Jesús; Iglesias Rey, Ramón; Taboada Antelo, Pablo (MDPI, 2016)
      A new ligand H3L, with internal compartments for allocating 3d metal ions and external donors to bind 4f ions, was synthesized and completely characterized. Reaction of H3L with zinc(II) and gadolin ium(III) salts allows ...
    • Hybrid Methacrylated Gelatin and Hyaluronic Acid Hydrogel Scaffolds. Preparation and Systematic Characterization for Prospective Tissue Engineering Applications 

      Velasco Rodríguez, Brenda; Diaz Vidal, Tania; Rosales Rivera, Luis Carlos; García González, Carlos Alberto; Álvarez Lorenzo, Carmen Isabel; Al-Modlej, Abeer; Domínguez Arca, Vicente; Prieto Estévez, Gerardo; Barbosa Fernández, Silvia; Soltero Martinez, José Félix Armando; Taboada Antelo, Pablo (MDPI, 2021)
      Hyaluronic acid (HA) and gelatin (Gel) are major components of the extracellular matrix of different tissues, and thus are largely appealing for the construction of hybrid hydrogels to combine the favorable characteristics ...
    • NIR-Emitting Alloyed CdTeSe QDs and Organic Dye Assemblies: A Nontoxic, Stable, and Efficient FRET System 

      Ramírez Herrera, Doris E.; Rodríguez Velázquez, Eustolia; Alatorre Meda, Manuel; Paraguay Delgado, Francisco; Tirado Guízar, Antonio; Taboada Antelo, Pablo; Pina Luis, Georgina (MDPI, 2018)
      In the present work, we synthesize Near Infrared (NIR)-emitting alloyed mercaptopropionic acid (MPA)-capped CdTeSe quantum dots (QDs) in a single-step one-hour process, without the use of an inert atmosphere or any ...
    • Probing the Occurrence of Soluble Oligomers through Amyloid Aggregation Scaling Laws 

      Silva, Alexandra; Sárkány, Zsuzsa; Fraga, Joana S.; Taboada Antelo, Pablo; Ribeiro, Sandra Macedo; Martins, Pedro M. (MDPI, 2018)
      Drug discovery frequently relies on the kinetic analysis of physicochemical reactions that are at the origin of the disease state. Amyloid fibril formation has been extensively investigated in relation to prevalent and ...
    • Protein Expression Knockdown in Cancer Cells Induced by a Gemini Cationic Lipid Nanovector with Histidine-Based Polar Heads 

      Sánchez Arribas, Natalia; Martínez Negro, María; Villar Álvarez, Eva María; Pérez, Lourdes; Osío Barcina, José; Aicart, Emilio; Taboada Antelo, Pablo; Guerrero Martínez, Andrés; Junquera, Elena (MDPI, 2020)
      A histidine-based gemini cationic lipid, which had already demonstrated its efficiency as a plasmid DNA (pDNA) nanocarrier, has been used in this work to transfect a small interfering RNA (siRNA) into cancer cells. In ...
    • SiRNA silencing by chemically modified biopolymeric nanovectors 

      Villar Álvarez, Eva María; Leal, Baltazar H.; Martínez González, Raquel; Pardo Montero, Alberto; Al-Qadi, Sonia; Juárez, Josué; Váldez, Miguel A.; Cambón Freire, Adriana; Barbosa Fernández, Silvia; Taboada Antelo, Pablo (American Chemical Society, 2019)
      The ability to specifically silence genes by RNA interference has an enormous potential for treating genetic diseases. However, different drawbacks such as short interfering RNA (siRNA) degradability by serum nucleases and ...
    • Syringeable Self-Organizing Gels that Trigger Gold Nanoparticle Formation for Localized Thermal Ablation 

      Cabana Montenegro, Sonia; Barbosa Fernández, Silvia; Taboada Antelo, Pablo; Concheiro Nine, Ángel Joaquín; Álvarez Lorenzo, Carmen Isabel (MDPI, 2019)
      Block copolymer dispersions that form gels at body temperature and that additionally are able to reduce a gold salt to nanoparticles (AuNPs) directly in the final formulation under mild conditions were designed as hybrid ...





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