Now showing items 1-16 of 16

    • Antireflection self-reference method based on ultrathin metallic nanofilms for improving terahertz reflection spectroscopy 

      Lai, Weien; Cao, Haibing; Yang, Jun; Deng, Guangsheng; Yin, Zhiping; Zhang, Qian; Pelaz García, Beatriz; Pino, Pablo del (The Optical Society, 2018)
      We present the potential of an antireflection self-reference method based on ultrathin tantalum nitride (TaN) nanofilms for improving terahertz (THz) reflection spectroscopy. The antireflection self-reference method is ...
    • Aqueous Stable Gold Nanostar/ZIF‐8 Nanocomposites for Light‐Triggered Release of Active Cargo Inside Living Cells 

      Carrillo Carrión, Carolina; Martínez González, Raquel; Navarro Poupard, María Fernanda; Pelaz García, Beatriz; Polo Tobajas, Ester; Arenas-Vivo, Ana; Olgiati, Alessandro; Taboada Antelo, Pablo; Soliman, Mahmoud G.; Catalán, Úrsula; Fernández-Castillejo, Sara; Solà, Rosa; Parak, Wolfgang J.; Horcajada, Patricia; Alvarez-Puebla, Ramon A.; Pino, Pablo del (Wiley, 2019-05-20)
      A plasmonic core–shell gold nanostar/zeolitic‐imidazolate‐framework‐8 (ZIF‐8) nanocomposite was developed for the thermoplasmonic‐driven release of encapsulated active molecules inside living cells. The nanocomposites were ...
    • Core-Shell Palladium/MOF Platforms as Diffusion-Controlled Nanoreactors in Living Cells and Tissue Models 

      Martínez González, Raquel; Carrillo Carrión, Carolina; Destito, Paolo; Álvarez Lorenzo, Aitor; Tomás Gamasa, María; Pelaz García, Beatriz; López García, Fernando; Mascareñas Cid, José Luis; Pino González de la Higuera, Pablo Alfonso del (Cell Press, 2020)
      Translating the potential of transition metal catalysis to biological and living environments promises to have a profound impact in chemical biology and biomedicine. A major challenge in the field is the creation of ...
    • Direct protein quantification in complex sample solutions by surface-engineered nanorod probes 

      Schrittwieser, Stefan; Pelaz García, Beatriz; Parak, Wolfgang J.; Lentijo-Mozo, Sergio; Soulantica, Katerina; Dieckhoff, Jan; Ludwig, Frank; Schotter, Joerg (Springer Nature, 2017)
      Detecting biomarkers from complex sample solutions is the key objective of molecular diagnostics. Being able to do so in a simple approach that does not require laborious sample preparation, sophisticated equipment and ...
    • Enhanced Terahertz Radiation Generation of Photoconductive Antennas Based on Manganese Ferrite Nanoparticles 

      Lai, Weien; Abdulmunem, Oday Mazin; Pino, Pablo del; Pelaz García, Beatriz; Parak, Wolfgang J.; Zhang, Qian; Zhang, Huaiwu (Springer Nature, 2017)
      This paper presents a significant effect of manganese ferrite nanoparticles (MnFe2O4 NPs) on the increase of the surface photoconductivity of semiconductors. Herein, the optical characterization of photo-excited carriers ...
    • High-yield halide-assisted synthesis of metal–organic framework UiO-based nanocarriers 

      Ceballos Guzmán, Manuel; Cedrún-Morales, Manuela; Rodríguez Pérez, Manuel; Funes-Hernando, Samuel; Vila Fungueiriño, José Manuel; Zampini, Giulia; Polo Tobajas, Ester; Pino, Pablo del; Pelaz García, Beatriz (Royal Society of Chemistry, 2022)
      The synthesis of nanosized metal–organic frameworks (NMOFs) is requisite for their application as injectable drug delivery systems (DDSs) and other biorelevant purposes. Herein, we have critically examined the role of ...
    • In situ detection of the protein corona in complex environments 

      Carril, Mónica; Prado, Daniel; Pino, Pablo del; Carrillo Carrión, Carolina; Gallego, Marta; Parak, Wolfgang J. (Springer Nature, 2017)
      Colloidal nanoparticles (NPs) are a versatile potential platform for in vivo nanomedicine. Inside blood circulation, NPs may undergo drastic changes, such as by formation of a protein corona. The in vivo corona cannot be ...
    • In vivo degeneration and the fate of inorganic nanoparticles 

      Feliu, Neus; Docter, Dominic; Heine, Markus; Pino, Pablo del; Ashraf, Sumaira; Kolosnjaj-Tabi, Jelena; Macchiarini, Paolo; Nielsen, Peter; Alloyeau, Damien; Gazeau, Florence; Stauber, Roland H.; Parak, Wolfgang J. (Royal Society of Chemistry, 2016)
      What happens to inorganic nanoparticles (NPs), such as plasmonic gold or silver, superparamagnetic iron oxide, or fluorescent quantum dot NPs after they have been administrated to a living being? This review discusses ...
    • Intracellular Delivery of Biologically-Active Fungal Metabolite Gliotoxin Using Magnetic Nanoparticles 

      Comas, Laura; Polo Tobajas, Ester; Domingo, M. Pilar; Hernández, Yulán; Arias, Maykel; Esteban, Patricia; Martínez-Lostao, Luis; Pardo, Julián; Martínez de la Fuente, Jesús; Gálvez, Eva M. (MDPI, 2019)
      Gliotoxin (GT), a secondary metabolite produced by Aspergillus molds, has been proposed as a potential anti-tumor agent. Here we have developed a nanoparticle approach to enhance delivery of GT in tumor cells and establish ...
    • Investigating Possible Enzymatic Degradation on Polymer Shells around Inorganic Nanoparticles 

      Zhu, Lin; Pelaz García, Beatriz; Chakraborty, Indranath; Parak, Wolfgang J. (Universidade de Santiago de Compostela, 2019)
      Inorganic iron oxide nanoparticle cores as model systems for inorganic nanoparticles were coated with shells of amphiphilic polymers, to which organic fluorophores were linked with different conjugation chemistries, including ...
    • Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo 

      Pérez-Hernández, Marta; Moros, María; Stepien, Grazyna; Pino, Pablo del; Menao, Sebastián; Heras, Marcelo de las; Arias, Maykel; Mitchell, Scott G.; Pelaz García, Beatriz; Gálvez, Eva M.; Martínez de la Fuente, Jesús; Pardo, Julián (BioMed Central, 2017)
      Background The special physicochemical properties of gold nanoprisms make them very useful for biomedical applications including biosensing and cancer therapy. However, it is not clear how gold nanoprisms may affect ...
    • Nanoparticles engineered to bind cellular motors for efficient delivery 

      Dalmau-Mena, Inmaculada; Pino, Pablo del; Pelaz García, Beatriz; Cuesta-Geijo, Miguel Ángel; Galindo, Inmaculada; Moros, María; Martínez de la Fuente, Jesús; Alonso, Covadonga (BioMed Central, 2018)
      Background Dynein is a cytoskeletal molecular motor protein that transports cellular cargoes along microtubules. Biomimetic synthetic peptides designed to bind dynein have been shown to acquire dynamic properties such as ...
    • Nanoscale metal–organic frameworks as key players in the context of drug delivery: evolution toward theranostic platforms 

      Carrillo Carrión, Carolina (Springer, 2020-01)
      Metal–organic frameworks (MOFs) have emerged as one of the most fascinating libraries of porous materials with a huge potential in very diverse application areas. In particular, the bioanalytical and biomedical fields have ...
    • New Approaches in Nanomedicine for Ischemic Stroke 

      Correa Paz, Clara; Silva Candal, Andrés da; Polo Tobajas, Ester; Parcq, Jerome; Vivien, Denis; Maysinger, Dusica; Pelaz García, Beatriz; Campos Pérez, Francisco (MDPI, 2021)
      Ischemic stroke, caused by the interruption of blood flow to the brain and subsequent neuronal death, represents one of the main causes of disability in developed countries. Therapeutic methods such as recanalization ...
    • Plasmonic-assisted thermocyclizations in living cells using metal−organic framework based nanoreactors 

      Carrillo Carrión, Carolina; Martínez González, Raquel; Polo Tobajas, Ester; Tomás Gamasa, María; Destito, Paolo; Ceballos, Manuel; Pelaz García, Beatriz; López García, Fernando; Mascareñas Cid, José Luis; Pino, Pablo del (ACS, 2021)
      We describe a microporous plasmonic nanoreactor to carry out designed near-infrared (NIR)-driven photothermal cyclizations inside living cells. As a proof of concept, we chose an intramolecular cyclization that is based ...
    • Study of Fluorinated Quantum Dots-Protein Interactions at the Oil/Water Interface by Interfacial Surface Tension Changes 

      Carrillo Carrión, Carolina; Gallego, Marta; Parak, Wolfgang J.; Carril, Mónica (MDPI, 2018)
      Understanding the interaction of nanoparticles with proteins and how this interaction modifies the nanoparticles’ surface is crucial before their use for biomedical applications. Since fluorinated materials are emerging ...





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