• Short oligoalanine helical peptides for supramolecular nanopore assembly and protein cytosolic delivery 

  Pazo Pascual, Marta; Salluce, Giulia; Lostalé Seijo, Irene; Juanes Carrasco, María Luisa; González García, Francisco; García Fandiño, Rebeca; Montenegro García, Javier (Royal Society of Chemistry, 2021)

  In this work we report a rational design strategy for the identification of new peptide prototypes for the non-disruptive supramolecular permeation of membranes and the transport of different macromolecular giant cargos. ...

• Curcumin–Coumarin Hybrid Analogues as Multitarget Agents in Neurodegenerative Disorders 

  Quezada González, Elías Neftalí; Rodríguez Enríquez, Fernanda; Laguna Francia, María de los Reyes; Cutrín Gómez, Elena; Otero Espinar, Francisco Javier; Uriarte Villares, Eugenio; Viña Castelao, María Dolores (MDPI, 2021)

  Neurodegenerative diseases have a complex nature which highlights the need for multitarget ligands to address the complementary pathways involved in these diseases. Over the last decade, many innovative curcumin-based ...

• Astrocyte Clocks and Glucose Homeostasis 

  Barca Mayo, Olga; López Pérez, Miguel Antonio (Frontiers Media, 2021)

  The endogenous timekeeping system evolved to anticipate the time of the day through the 24 hours cycle of the Earth’s rotation. In mammals, the circadian clock governs rhythmic physiological and behavioral processes, ...

• Satellitome Analysis of the Pacific Oyster Crassostrea gigas Reveals New Pattern of Satellite DNA Organization, Highly Scattered across the Genome 

  Tunjić Cvitanić, Monika; Pasantes, Juan J.; García Souto, Daniel; Cvitanić, Tonči; Plohl, Miroslav; Šatović Vukšić, Eva (MDPI, 2021)

  Several features already qualified the invasive bivalve species Crassostrea gigas as a valuable non-standard model organism in genome research. C. gigas is characterized by the low contribution of satellite DNAs (satDNAs) ...

• Caloric Restriction Prevents Metabolic Dysfunction and the Changes in Hypothalamic Neuropeptides Associated with Obesity Independently of Dietary Fat Content in Rats 

  Martín, Marina; Rodríguez, Amaia; Gómez Ambrosi, Javier; Ramírez, Beatriz; Becerril, Sara; Catalán, Victoria; López Pérez, Miguel Antonio; Diéguez González, Carlos; Frühbeck, Gema; Burrell, María Ángela (MDPI, 2021)

  Energy restriction is a first therapy in the treatment of obesity, but the underlying biological mechanisms have not been completely clarified. We analyzed the effects of restriction of high-fat diet (HFD) on weight loss, ...

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