Search
Now showing items 1-10 of 12
Photophysical study of Thioflavin T as fluorescence marker of amyloid fibrils
(Elsevier, 2014)
Thioflavin T is a highly sensitive fluorescent marker of amyloid fibrils that has been widely used for in vitro biomedical assays. However, neither its complex photophysical behavior nor its binding mode to amyloid fibrils ...
A model for monomer and micellar concentrations in surfactant solutions: application to conductivity, NMR, diffusion, and surface tension data
(Elsevier, 2012)
An empirical model for the concentrations of monomeric and micellized surfactants in solution is presented as a consistent approach for the quantitative analysis of data obtained with different experimental techniques from ...
Host-Guest Complexation Studied by Fluorescence Correlation Spectroscopy: Adamantane–Cyclodextrin Inclusion
(MDPI, 2010)
The host-guest complexation between an Alexa 488 labelled adamantane derivative and β-cyclodextrin is studied by Fluorescence Correlation Spectroscopy (FCS). A 1:1 complex stoichiometry and a high association equilibrium ...
Fluorescence Emission of Pyrene in Surfactant Solutions
(Elsevier, 2015)
The systematic description of the complex photophysical behavior of pyrene in surfactant solutions in combination with
a quantitative model for the surfactant concentrations reproduces with high accuracy the steady-state ...
Towards Ratiometric Sensing of Amyloid Fibrils In Vitro
(Wiley, 2015)
The aggregation of amyloid‐β peptide and its accumulation in the human brain has an important role in the etiology of Alzheimer’s disease. Thioflavin T has been widely used as a fluorescent marker for these amyloid aggregates. ...
Critical aggregation concentration for the formation of early Amyloid-β (1–42) oligomers
(Nature Publishing Group, 2018-01-29)
The oligomers formed during the early steps of amyloid aggregation are thought to be responsible for the neurotoxic damage associated with Alzheimer’s disease. It is therefore of great interest to characterize this early ...
Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents
(Nature Publishing Group, 2019)
The solubilization of membranes by detergents is critical for many technological applications and has become widely used in biochemistry research to induce cell rupture, extract cell constituents, and to purify, reconstitute ...
Host-guest complexation studied by fluorescence correlation spectroscopy: adamantane–cyclodextrin inclusion
(MDPI, 2010)
The host-guest complexation between an Alexa 488 labelled adamantane
derivative and β-cyclodextrin is studied by Fluorescence Correlation Spectroscopy (FCS). A
1:1 complex stoichiometry and a high association equilibrium ...
Fluorescence-Labeled Bis-benzamidines as Fluorogenic DNA Minor-Groove Binders: Photophysics and Binding Dynamics
(WILEY-VCH Verlag GmbH, 2014-11-21)
In recent decades there has been great interest in the design of highly sensitive sequence-specific DNA binders. The eligibility of the binder depends on the magnitude of the fluorescence increase upon binding, related to ...
In Vivo Theranostics at the Peri-Infarct Region in Cerebral Ischemia
(Ivyspring International Publisher, 2014)
The use of theranostics in neurosciences has been rare to date because of the limitations imposed on the free delivery of substances to the brain by the blood-brain barrier. Here we report the development of a theranostic ...